With MPB treatment, the trick is to start as soon as possible. While Minoxidil and Finasteride have a big impact in the battle against that androgen, DHT, they can only do so much. If you’re completely bald and have been for a long time, it is unlikely that treatment will work. DHT will have made the follicles unable to produce hair – and permanent hair loss is the result. Start treatment as soon as you can.